Female brain’s G-spot found

by limbic on June 27, 2006

Female brain’s G-spot found!: “

The heterosexual female brain’s g-spot has been found by a team of scientists. After years of struggle, this breakthrough will finally allow us to render a woman unmoved by a man’s advances. The study pinpoints not only the necessary hormone, but the place in the brain where arousal happens.

Sonoko Ogawa of the University of Tsukuba in Japan and a team of American colleagues blocked the flow of oestrogen to the ventromedial nucleus (VMN) of mice. Using tiny bits of genetic material - small hairpin RNAs - to stop production of oestrogen receptor alpha, they prevented oestrogen from finding a home in the VMN. With their VNM deprived of any oestrogen, the lady mice refused to have sex.

‘They became extremely aggressive towards males, and started biting and kicking when males approached,’ says Ogawa.

An amazing - and rather racy - video compares a normal mouse’s reaction to a paramour’s advances with that of an oestrogen-free lady mouse. While one mouse is only too happy to make whoopee, her oestrogen-starved friend furiously runs away from her suitor.

‘Disruption of normal oestrogen signaling only in this region while leaving it intact elsewhere in the brain and the rest of the body is sufficient to completely block normal female courtship behavior,’ says Ogawa.

Scientists have long suspected that the VMN was the home of female arousal, but previous experiments used mice genetically engineered to have no oestrogen receptor alpha at all. These previous efforts only proved that oestrogen was necessary. By blocking signals just to the VMN, Ogawa has proved it to be where the magic happens in a female’s brain.

(Via Sploid.)